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Built by scientists who have done it before.

Founded in 2023 in Ann Arbor, Michigan, Signal Bioscience has a singular focus: make high-level multiplex PCR accessible to every lab, on the instruments they already own.

Team With Deep Domain Expertise

Our team brings together serial entrepreneurs, veteran assay developers, and deep oligo chemistry expertise — united by a mission to democratize precision diagnostics.

John Cunningham, MBA

John Cunningham, MBA

CEO & Co-Founder
  • Founder and CEO of RapidBio (300K+ samples, $20M+ revenue)
  • COO of Functional Fluidics
  • Technology Transfer at University of Michigan
Vladimir Makarov, Ph.D.

Vladimir Makarov, Ph.D.

CSO & Co-Founder
  • Co-Founder of Rubicon Genomics (acquired by Takara Bio)
  • Co-Founder of Swift Biosciences (acquired by IDT/Danaher)
  • 50+ publications and 23 patents
Adam McCoy, Ph.D.

Adam McCoy, Ph.D.

VP of Research & Development
  • Assoc. Director, Specialty Reagents at Bio-Rad
  • Director, R&D at LGC Biosearch Technologies
  • Head, Single-Cell Chemistry at Celsee (acquired by Bio-Rad)
Karl Spork, M.S.

Karl Spork, M.S.

Scientist
  • Staff Scientist at IDT
  • Senior Research Associate at Swift Biosciences
Niloufar Mertz, Ph.D.

Niloufar Mertz, Ph.D.

Senior Scientist
  • Senior Scientist at Bio-Rad
  • Research Assistant at Kansas State University
Eric Pomaranski, Ph.D.

Eric Pomaranski, Ph.D.

Senior Scientist
  • Senior Scientist at Bio-Rad
  • Postdoctoral Researcher at UC Davis
Emanuel Vacchiano, J.D., Ph.D.

Emanuel Vacchiano, J.D., Ph.D.

Legal Counsel
  • Founder, Double Helix Law
  • Lead Patent Counsel at Thermo Fisher / Life Technologies
50+
Publications
23
Patents
2
Successful Exits
2023
Founded

Science-backed. Partner-driven.

We’re actively partnering with diagnostics companies, platform developers, and investors to accelerate the impact of Signal Chemistry.

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